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Popular San Francisco to Cayman Islands flight itineraries

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. Additional bag and optional fees for products and services may apply.

American Airlines flights from San Francisco to Cayman Islands

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From
To
Fare type
Travel dates
Price
San Francisco (SFO)Grand Cayman (GCM)Round trip
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Economy		03/18/26 - 03/31/26

from

$583Fare subject to changes

Updated: 17 hours ago

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From
To
Fare type
Travel dates
Price
Booking
San Francisco (SFO)Chicago (ORD)Round trip
I
Premium Economy		07/10/26 - 07/15/26

from

$1,300Fare subject to changes

Updated: 14 hours ago

San Francisco (SFO)Tokyo (TYO)Round trip
I
Premium Economy		03/01/26 - 09/15/26

from

$3,356Fare subject to changes

Updated: 7 hours ago

San Francisco (SFO)Tokyo (HND)Round trip
I
Premium Economy		05/25/26 - 06/05/26

from

$3,678Fare subject to changes

Updated: 3 hours ago

San Francisco (SFO)New York (JFK)Round trip
I
Premium Economy		04/15/26 - 04/29/26

from

$1,181Fare subject to changes

Updated: 8 hours ago

San Francisco (SFO)Miami (MIA)Round trip
I
Premium Economy		06/20/26 - 06/26/26

from

$1,286Fare subject to changes

Updated: 17 hours ago

San Francisco (SFO)New York (NYC)Round trip
I
Premium Economy		03/27/26 - 04/04/26

from

$1,440Fare subject to changes

Updated: 17 hours ago

San Francisco (SFO)London (LHR)Round trip
I
Premium Economy		04/01/26 - 04/09/26

from

$1,811Fare subject to changes

Updated: 16 hours ago

San Francisco (SFO)Boston (BOS)Round trip
I
Premium Economy		07/08/26 - 07/14/26

from

$1,501Fare subject to changes

Updated: 28 minutes ago

San Francisco (SFO)Madrid (MAD)Round trip
I
Premium Economy		02/25/26 - 03/04/26

from

$1,432Fare subject to changes

Updated: 3 hours ago

San Francisco (SFO)Tokyo (NRT)Round trip
I
Premium Economy		06/09/26 - 06/30/26

from

$3,954Fare subject to changes

Updated: 15 hours ago

San Francisco (SFO)Sydney (SYD)Round trip
I
Premium Economy		06/04/26 - 06/13/26

from

$4,267Fare subject to changes

Updated: 15 hours ago

San Francisco (SFO)Barcelona (BCN)Round trip
I
Premium Economy		02/25/26 - 03/04/26

from

$1,706Fare subject to changes

Updated: 10 hours ago

San Francisco (SFO)Paris (CDG)Round trip
I
Premium Economy		04/29/26 - 05/09/26

from

$2,128Fare subject to changes

Updated: 12 hours ago

San Francisco (SFO)Honolulu (HNL)Round trip
I
Premium Economy		03/25/26 - 03/31/26

from

$2,056Fare subject to changes

Updated: 9 hours ago

San Francisco (SFO)Dublin (DUB)Round trip
I
Premium Economy		07/21/26 - 08/03/26

from

$1,724Fare subject to changes

Updated: 9 hours ago

San Francisco (SFO)Chicago (CHI)Round trip
I
Premium Economy		07/04/26 - 07/12/26

from

$1,735Fare subject to changes

Updated: 17 hours ago

San Francisco (SFO)London (LON)Round trip
I
Premium Economy		04/27/26 - 05/08/26

from

$2,041Fare subject to changes

Updated: 12 hours ago

San Francisco (SFO)Athens (ATH)Round trip
I
Premium Economy		06/22/26 - 07/03/26

from

$3,067Fare subject to changes

Updated: 12 hours ago

San Francisco (SFO)Buenos Aires (EZE)Round trip
I
Premium Economy		03/18/26 - 03/27/26

from

$3,172Fare subject to changes

Updated: 17 hours ago

San Francisco (SFO)Hong Kong (HKG)Round trip
I
Premium Economy		04/27/26 - 08/20/26

from

$3,457Fare subject to changes

Updated: 10 hours ago

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Dallas (DFW)to

London (LHR)
04/26/26 - 05/12/26

Round trip

Economy

from
$824Fare subject to changes
Updated: 14 minutes ago

Dallas (DFW)to

New York (LGA)
04/22/26 - 04/25/26

Round trip

Economy

from
$179Fare subject to changes
Updated: 9 minutes ago

Los Angeles (LAX)to

Melbourne (MEL)
04/05/26 - 04/12/26

Round trip

Economy

from
$1,381Fare subject to changes
Updated: 2 minutes ago

Dallas (DFW)to

Los Angeles (LAX)
03/18/26 - 03/24/26

Round trip

Economy

from
$259Fare subject to changes
Updated: 1 hour ago

Los Angeles (LAX)to

New York (JFK)
05/13/26 - 05/15/26

Round trip

Economy

from
$277Fare subject to changes
Updated: 2 hours ago

Dallas (DFW)to

Miami (MIA)
05/16/26 - 05/20/26

Round trip

Economy

from
$270Fare subject to changes
Updated: 1 hour ago

Phoenix (PHX)to

Flagstaff (FLG)
02/20/26 - 02/21/26

Round trip

Economy

from
$511Fare subject to changes
Updated: 1 hour ago

Philadelphia (PHL)to

Orlando (MCO)
04/07/26 - 04/08/26

Round trip

Economy

from
$199Fare subject to changes
Updated: 7 minutes ago

Dallas (DFW)to

Las Vegas (LAS)
03/17/26 - 03/18/26

Round trip

Economy

from
$259Fare subject to changes
Updated: 2 hours ago

Dallas (DFW)to

Orlando (MCO)
04/01/26 - 04/08/26

Round trip

Economy

from
$209Fare subject to changes
Updated: 32 minutes ago

Dallas (DFW)to

Cancun (CUN)
05/04/26 - 05/08/26

Round trip

Economy

from
$325Fare subject to changes
Updated: 33 minutes ago

Philadelphia (PHL)to

Tampa (TPA)
03/25/26 - 03/31/26

Round trip

Economy

from
$199Fare subject to changes
Updated: 42 minutes ago

New York (JFK)to

London (LHR)
02/20/26 - 02/25/26

Round trip

Economy

from
$506Fare subject to changes
Updated: 1 hour ago

Phoenix (PHX)to

Miami (MIA)
03/31/26 - 04/04/26

Round trip

Economy

from
$222Fare subject to changes
Updated: 1 hour ago

Chicago (ORD)to

Phoenix (PHX)
04/25/26 - 05/02/26

Round trip

Economy

from
$177Fare subject to changes
Updated: 40 minutes ago

Los Angeles (LAX)to

Tokyo (TYO)
04/27/26 - 05/04/26

Round trip

Economy

from
$865Fare subject to changes
Updated: 1 hour ago

Miami (MIA)to

Madrid (MAD)
04/15/26 - 04/22/26

Round trip

Economy

from
$427Fare subject to changes
Updated: 2 hours ago

Philadelphia (PHL)to

Fort Lauderdale (FLL)
03/14/26 - 03/18/26

Round trip

Economy

from
$167Fare subject to changes
Updated: 1 hour ago

Los Angeles (LAX)to

Tokyo (HND)
03/03/26 - 03/11/26

Round trip

Economy

from
$860Fare subject to changes
Updated: 1 hour ago

Los Angeles (LAX)to

Denver (DEN)
05/14/26 - 05/15/26

Round trip

Economy

from
$259Fare subject to changes
Updated: 1 hour ago

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QA FE BUG-2112 Prepro__ Los Angeles

QA FE BUG-2112 Prepro__ Washington, D.C.

QA FE BUG-2112 Prepro__ London

QA FE BUG-2112 Prepro__ New York

QA FE BUG-2112 Prepro__ Melbourne

QA FE BUG-2112 Prepro__ Austin

QA FE BUG-2112 Prepro__ Flagstaff

QA FE BUG-2112 Prepro__ Orlando

QA FE BUG-2112 Prepro__ Las Vegas

QA FE BUG-2112 Prepro__ Cancun

QA FE BUG-2112 Prepro__ Tampa

QA FE BUG-2112 Prepro__ Phoenix

QA FE BUG-2112 Prepro__ Tokyo

QA FE BUG-2112 Prepro__ Madrid

QA FE VGA-2704 Round trip on Economy

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  • Los Angeles (LAX)to

    New York (JFK)
    05/03/26 - 05/05/26
    from
    $277Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

    Dallas (DFW)to

    Miami (MIA)
    05/16/26 - 05/20/26
    from
    $270Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

    Phoenix (PHX)to

    Flagstaff (FLG)
    02/20/26 - 02/21/26
    from
    $511Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

    Philadelphia (PHL)to

    Orlando (MCO)
    04/07/26 - 04/08/26
    from
    $199Fare subject to changes
    Updated: 7 minutes ago
    Round trip
    Economy

  • Dallas (DFW)to

    Las Vegas (LAS)
    03/17/26 - 03/18/26
    from
    $259Fare subject to changes
    Updated: 2 hours ago
    Round trip
    Economy

    Dallas (DFW)to

    Orlando (MCO)
    04/01/26 - 04/08/26
    from
    $209Fare subject to changes
    Updated: 32 minutes ago
    Round trip
    Economy

    Dallas (DFW)to

    Cancun (CUN)
    04/19/26 - 04/30/26
    from
    $325Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

    Philadelphia (PHL)to

    Tampa (TPA)
    03/24/26 - 04/01/26
    from
    $199Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

  • New York (JFK)to

    London (LHR)
    02/20/26 - 02/25/26
    from
    $506Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

    Phoenix (PHX)to

    Miami (MIA)
    03/31/26 - 04/04/26
    from
    $222Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

    Chicago (ORD)to

    Phoenix (PHX)
    04/25/26 - 05/02/26
    from
    $177Fare subject to changes
    Updated: 40 minutes ago
    Round trip
    Economy

    Los Angeles (LAX)to

    Tokyo (TYO)
    04/27/26 - 05/04/26
    from
    $865Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

  • Miami (MIA)to

    Madrid (MAD)
    04/15/26 - 04/22/26
    from
    $427Fare subject to changes
    Updated: 2 hours ago
    Round trip
    Economy

    Philadelphia (PHL)to

    Fort Lauderdale (FLL)
    03/17/26 - 03/21/26
    from
    $167Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

    Los Angeles (LAX)to

    Tokyo (HND)
    03/03/26 - 03/11/26
    from
    $860Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

    Los Angeles (LAX)to

    Denver (DEN)
    05/14/26 - 05/15/26
    from
    $259Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy