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Popular Des Moines to Mexico flight itineraries

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  • Des Moines (DSM)to

    Cozumel (CZM)
    04/30/25 - 05/07/25
    from
    $505Fare subject to changes
    Updated: 24 minutes ago
    Round trip
    I
    Economy

    Des Moines (DSM)to

    Mexico City (MEX)
    05/06/25 - 05/13/25
    from
    $488Fare subject to changes
    Updated: 2 hours ago
    Round trip
    I
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. Additional bag and optional fees for products and services may apply.

American Airlines flights from Des Moines to Mexico

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From
To
Fare type
Travel dates
Price
Des Moines (DSM)Cancun (CUN)Round trip
I
Economy		09/13/25 - 09/17/25

from

$423Fare subject to changes

Updated: 21 hours ago

Des Moines (DSM)Cabo San Lucas (SJD)Round trip
I
Economy		09/23/25 - 09/30/25

from

$443Fare subject to changes

Updated: 21 hours ago

Des Moines (DSM)Puerto Vallarta (PVR)Round trip
I
Economy		05/14/25 - 05/21/25

from

$496Fare subject to changes

Updated: 11 hours ago

Des Moines (DSM)Guadalajara (GDL)Round trip
I
Economy		05/05/25 - 05/12/25

from

$470Fare subject to changes

Updated: 8 hours ago

Des Moines (DSM)Cozumel (CZM)Round trip
I
Economy		07/15/25 - 07/22/25

from

$493Fare subject to changes

Updated: 24 minutes ago

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From
To
Fare type
Travel dates
Price
Booking
Des Moines (DSM)London (LHR)Round trip
I
Premium Economy		05/20/25 - 05/27/25

from

$1,997Fare subject to changes

Updated: 15 hours ago

Des Moines (DSM)Honolulu (HNL)Round trip
I
Premium Economy		09/04/25 - 09/15/25

from

$1,853Fare subject to changes

Updated: 1 hour ago

Des Moines (DSM)Maui (OGG)Round trip
I
Premium Economy		08/25/25 - 09/01/25

from

$1,903Fare subject to changes

Updated: 17 hours ago

Des Moines (DSM)Rome (FCO)Round trip
I
Premium Economy		10/15/25 - 10/24/25

from

$2,548Fare subject to changes

Updated: 14 hours ago

Des Moines (DSM)Kauai (LIH)Round trip
I
Premium Economy		04/29/25 - 05/06/25

from

$1,473Fare subject to changes

Updated: 1 hour ago

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