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Popular Des Moines to Mexico flight itineraries

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. Additional bag and optional fees for products and services may apply.

American Airlines flights from Des Moines to Mexico

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From
To
Fare type
Travel dates
Price
Des Moines (DSM)Cancun (CUN)Round trip
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Economy		08/13/25 - 08/20/25

from

$456Fare subject to changes

Updated: 9 hours ago

Des Moines (DSM)Cabo San Lucas (SJD)Round trip
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Economy		08/12/25 - 08/19/25

from

$325Fare subject to changes

Updated: 4 hours ago

Des Moines (DSM)Puerto Vallarta (PVR)Round trip
I
Economy		08/12/25 - 08/19/25

from

$499Fare subject to changes

Updated: 4 hours ago

Des Moines (DSM)Cozumel (CZM)Round trip
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Economy		08/07/25 - 08/14/25

from

$522Fare subject to changes

Updated: 7 hours ago

Des Moines (DSM)Guadalajara (GDL)Round trip
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Economy		08/08/25 - 08/15/25

from

$539Fare subject to changes

Updated: 7 hours ago

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From
To
Fare type
Travel dates
Price
Booking
Des Moines (DSM)Honolulu (HNL)Round trip
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Premium Economy		11/11/25 - 11/22/25

from

$1,848Fare subject to changes

Updated: 3 hours ago

Des Moines (DSM)London (LHR)Round trip
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Premium Economy		09/23/25 - 09/30/25

from

$1,809Fare subject to changes

Updated: 5 hours ago

Des Moines (DSM)Maui (OGG)Round trip
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Premium Economy		07/11/25 - 07/18/25

from

$2,303Fare subject to changes

Updated: 8 hours ago

Des Moines (DSM)Rome (FCO)Round trip
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Premium Economy		10/01/25 - 10/08/25

from

$2,849Fare subject to changes

Updated: 5 hours ago

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QA FE Asset in CP VGA-2437