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Popular Des Moines to Mexico flight itineraries

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. Additional bag and optional fees for products and services may apply.

American Airlines flights from Des Moines to Mexico

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From
To
Fare type
Travel dates
Price
Des Moines (DSM)Cancun (CUN)Round trip
I
Economy		01/28/26 - 02/04/26

from

$486Fare subject to changes

Updated: 10 hours ago

Des Moines (DSM)Puerto Vallarta (PVR)Round trip
I
Economy		12/03/25 - 12/10/25

from

$556Fare subject to changes

Updated: 10 hours ago

Des Moines (DSM)Cabo San Lucas (SJD)Round trip
I
Economy		12/10/25 - 12/17/25

from

$556Fare subject to changes

Updated: 1 hour ago

Des Moines (DSM)Guadalajara (GDL)Round trip
I
Economy		11/25/25 - 12/02/25

from

$551Fare subject to changes

Updated: 3 hours ago

Des Moines (DSM)Mexico City (MEX)Round trip
I
Economy		02/05/26 - 02/12/26

from

$529Fare subject to changes

Updated: 53 minutes ago

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From
To
Fare type
Travel dates
Price
Booking
Des Moines (DSM)Maui (OGG)Round trip
I
Premium Economy		04/29/26 - 05/12/26

from

$1,998Fare subject to changes

Updated: 8 hours ago

Des Moines (DSM)Honolulu (HNL)Round trip
I
Premium Economy		02/23/26 - 03/01/26

from

$1,577Fare subject to changes

Updated: 4 hours ago

Des Moines (DSM)Rome (FCO)Round trip
I
Premium Economy		01/12/26 - 01/18/26

from

$1,608Fare subject to changes

Updated: 39 minutes ago

Des Moines (DSM)Kona (KOA)Round trip
I
Premium Economy		03/09/26 - 03/16/26

from

$2,312Fare subject to changes

Updated: 9 hours ago

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Dallas (DFW)to

New York (LGA)
12/09/25 - 12/12/25

Round trip

Economy

from
$199Fare subject to changes
Updated: 22 minutes ago

New York (JFK)to

London (LHR)
11/26/25 - 12/03/25

Round trip

Economy

from
$483Fare subject to changes
Updated: 2 hours ago

Phoenix (PHX)to

Miami (MIA)
12/11/25 - 12/18/25

Round trip

Economy

from
$167Fare subject to changes
Updated: 2 hours ago

Dallas (DFW)to

Miami (MIA)
01/24/26 - 02/01/26

Round trip

Economy

from
$147Fare subject to changes
Updated: 47 minutes ago

Dallas (DFW)to

London (LHR)
01/27/26 - 02/10/26

Round trip

Economy

from
$717Fare subject to changes
Updated: 28 minutes ago

Los Angeles (LAX)to

Tokyo (HND)
01/20/26 - 01/27/26

Round trip

Economy

from
$671Fare subject to changes
Updated: 1 hour ago

Los Angeles (LAX)to

New York (JFK)
01/08/26 - 01/13/26

Round trip

Economy

from
$217Fare subject to changes
Updated: 51 minutes ago

Dallas (DFW)to

Tokyo (HND)
01/30/26 - 02/06/26

Round trip

Economy

from
$1,289Fare subject to changes
Updated: 2 hours ago

Dallas (DFW)to

Los Angeles (LAX)
01/14/26 - 01/21/26

Round trip

Economy

from
$151Fare subject to changes
Updated: 2 hours ago

Dallas (DFW)to

Las Vegas (LAS)
12/09/25 - 12/13/25

Round trip

Economy

from
$131Fare subject to changes
Updated: 2 hours ago

Philadelphia (PHL)to

Orlando (MCO)
01/07/26 - 01/13/26

Round trip

Economy

from
$154Fare subject to changes
Updated: 2 hours ago

New York (NYC)to

Tokyo (HND)
11/24/25 - 12/01/25

Round trip

Economy

from
$1,405Fare subject to changes
Updated: 1 hour ago

San Francisco (SFO)to

Tokyo (HND)
01/21/26 - 01/28/26

Round trip

Economy

from
$796Fare subject to changes
Updated: 2 hours ago

Chicago (ORD)to

Miami (MIA)
01/13/26 - 01/20/26

Round trip

Economy

from
$157Fare subject to changes
Updated: 2 hours ago

Miami (MIA)to

Tokyo (HND)
11/23/25 - 12/04/25

Round trip

Economy

from
$1,906Fare subject to changes
Updated: 1 hour ago

Philadelphia (PHL)to

Tokyo (HND)
01/29/26 - 02/05/26

Round trip

Economy

from
$1,034Fare subject to changes
Updated: 2 hours ago

Chicago (ORD)to

Tokyo (HND)
01/21/26 - 01/28/26

Round trip

Economy

from
$1,134Fare subject to changes
Updated: 3 hours ago

Seattle (SEA)to

Tokyo (HND)
11/28/25 - 12/04/25

Round trip

Economy

from
$920Fare subject to changes
Updated: 2 hours ago

Las Vegas (LAS)to

Tokyo (HND)
01/30/26 - 02/12/26

Round trip

Economy

from
$650Fare subject to changes
Updated: 59 minutes ago

Phoenix (PHX)to

Tokyo (HND)
01/30/26 - 02/06/26

Round trip

Economy

from
$1,034Fare subject to changes
Updated: 3 hours ago

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QA FE BUG-2112 Prepro__ Miami

QA FE BUG-2112 Prepro__ Tokyo

QA FE BUG-2112 Prepro__ New York

QA FE BUG-2112 Prepro__ Los Angeles

QA FE BUG-2112 Prepro__ Las Vegas

QA FE BUG-2112 Prepro__ Orlando

QA FE BUG-2112 Prepro__ Amarillo

QA FE BUG-2112 Prepro__ Phoenix

QA FE BUG-2112 Prepro__ Cancun

QA FE BUG-2112 Prepro__ Sydney

QA FE BUG-2112 Prepro__ Melbourne

QA FE BUG-2112 Prepro__ Madrid

QA FE BUG-2112 Prepro__ Fort Lauderdale

QA FE BUG-2112 Prepro__ Chicago

QA FE BUG-2112 Prepro__ Boston

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