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Popular Grand Cayman to Panama flight itineraries

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. Additional bag and optional fees for products and services may apply.

Find more Grand Cayman to Panama deals

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights from Grand Cayman to Panama

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From
To
Fare type
Travel dates
Price
Grand Cayman (GCM)Panama City (PTY)Round trip
I
Economy
10/03/2026 - 17/03/2026

from

USD712Fare subject to changes

Updated: 3 hours ago

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From
To
Fare type
Travel dates
Price
Booking
Grand Cayman (GCM)London (LON)Round trip
I
Premium Economy
01/03/2026 - 06/03/2026

from

USD3,459Fare subject to changes

Updated: 16 hours ago

Grand Cayman (GCM)London (LHR)Round trip
I
Premium Economy
01/07/2026 - 10/08/2026

from

USD3,396Fare subject to changes

Updated: 16 hours ago

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Dallas (DFW)to

New York (LGA)
10/02/2026 - 11/02/2026

Round trip

Economy

from
USD195Fare subject to changes
Updated: 23 minutes ago

Dallas (DFW)to

Los Angeles (LAX)
17/02/2026 - 21/02/2026

Round trip

Economy

from
USD199Fare subject to changes
Updated: 49 minutes ago

New York (JFK)to

London (LHR)
24/02/2026 - 03/03/2026

Round trip

Economy

from
USD460Fare subject to changes
Updated: 1 hour ago

Dallas (DFW)to

Miami (MIA)
02/03/2026 - 09/03/2026

Round trip

Economy

from
USD205Fare subject to changes
Updated: 1 minute ago

Dallas (DFW)to

Las Vegas (LAS)
28/02/2026 - 03/03/2026

Round trip

Economy

from
USD159Fare subject to changes
Updated: 1 hour ago

Philadelphia (PHL)to

Orlando (MCO)
23/02/2026 - 26/02/2026

Round trip

Economy

from
USD179Fare subject to changes
Updated: 1 hour ago

Dallas (DFW)to

London (LHR)
11/03/2026 - 18/03/2026

Round trip

Economy

from
USD638Fare subject to changes
Updated: 1 hour ago

Phoenix (PHX)to

Miami (MIA)
09/02/2026 - 10/02/2026

Round trip

Economy

from
USD212Fare subject to changes
Updated: 1 hour ago

Los Angeles (LAX)to

New York (JFK)
20/02/2026 - 23/02/2026

Round trip

Economy

from
USD292Fare subject to changes
Updated: 1 hour ago

Dallas (DFW)to

Orlando (MCO)
16/02/2026 - 19/02/2026

Round trip

Economy

from
USD179Fare subject to changes
Updated: 2 minutes ago

Dallas (DFW)to

Cancun (CUN)
23/02/2026 - 26/02/2026

Round trip

Economy

from
USD472Fare subject to changes
Updated: 51 minutes ago

Philadelphia (PHL)to

Tampa (TPA)
21/02/2026 - 24/02/2026

Round trip

Economy

from
USD179Fare subject to changes
Updated: 1 hour ago

Chicago (ORD)to

Phoenix (PHX)
18/02/2026 - 11/03/2026

Round trip

Economy

from
USD177Fare subject to changes
Updated: 52 minutes ago

Philadelphia (PHL)to

Fort Lauderdale (FLL)
10/03/2026 - 31/03/2026

Round trip

Economy

from
USD137Fare subject to changes
Updated: 2 hours ago

Miami (MIA)to

Madrid (MAD)
27/01/2026 - 01/05/2026

Round trip

Economy

from
USD409Fare subject to changes
Updated: 1 hour ago

Philadelphia (PHL)to

Miami (MIA)
11/03/2026 - 18/03/2026

Round trip

Economy

from
USD189Fare subject to changes
Updated: 2 hours ago

Dallas (DFW)to

Phoenix (PHX)
10/02/2026 - 14/02/2026

Round trip

Economy

from
USD239Fare subject to changes
Updated: 1 hour ago

Charlotte (CLT)to

Las Vegas (LAS)
21/02/2026 - 25/03/2026

Round trip

Economy

from
USD319Fare subject to changes
Updated: 1 hour ago

Dallas (DFW)to

Amarillo (AMA)
18/02/2026 - 19/02/2026

Round trip

Economy

from
USD281Fare subject to changes
Updated: 2 hours ago

Chicago (ORD)to

Miami (MIA)
21/02/2026 - 28/02/2026

Round trip

Economy

from
USD189Fare subject to changes
Updated: 23 minutes ago

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